Amelanotic melanocytic tumors of the pinna in six F344 rats.
نویسندگان
چکیده
منابع مشابه
the effect of aqueous extract of garlic on formalin-induced pain in male rats
چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولInduction of Lung and Exocrine Pancreas Tumors in F344 Rats
The tobacco-specific A'-nitrosamines 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone (NNK) and 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanol (NNAL), as well as the /4reca-derived A'-nitrosoguvacoline (NG) were assayed for carcinogenicity in male F344 rats by lifetime adminis tration in the drinking water. Groups of 30 to 80 rats were treated with 0.5 ppm, 1.0 ppm, or 5.0 ppm of NNK; 5.0 npm of N...
متن کاملAn amelanotic dysplastic melanocytic nevus induced by vemurafenib.
Vemurafenib is a B-raf kinase inhibitor developed to treat metastatic melanoma in patients with the BRAF V600E mutation, which is found in 40% to 60% of patients with advanced melanoma. It acts by inhibiting the BRAF/MEK/ERK mitogenactivated protein kinase (MAPK) pathway at the BRAF/MEK step. Recent studies have reported that vemurafenib is associated with a 63% reduction in risk of death. Adve...
متن کاملSpindle cell melanocytic tumors
pseudoinclusions are sometimes evident and mild nuclear pleomorphism is typical. Mitoses are either absent or extremely infrequent. By definition dendritic cells are said not to be seen in this lesion. The growth pattern often presents a plexiform appearance, fascicles of nevus cells following the dermal appendages and neurovascular bundles. Perineural or endoneural extension is a very common f...
متن کاملThe role of alpha2u-globulin in ochratoxin A induced renal toxicity and tumors in F344 rats.
The mycotoxin ochratoxin A (OTA) was shown to be a potent kidney carcinogen in rats demonstrating a marked sex difference in the response. Compared to female rats, male rats had a 10-fold higher incidence of kidney carcinomas. The objective of this study was to investigate whether this sex difference in tumor response is due to an exacerbation of effect resulting from the interaction of the mal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 1991
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.53.291